Package of 90 pieces of Novartis Glivec. 400mg Imatinib per tablet. German distribution package.
Imatinib is a drug used to treat certain types of cancer. It is currently marketed by Novartis as Gleevec (USA) or Glivec (Europe/Australia) as its mesylate salt, imatinib mesilate (INN) (formerly called STI-571). It is used in treating chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GISTs) and other cancers. It is the first member of a new class of agents that act by specifically inhibiting a certain enzyme that is characteristic of a particular cancer cell, rather than non-specifically inhibiting and killing all rapidly dividing cells. In CML, the enzyme tyrosine kinase is stuck in the "on" position. Imatinib binds to the site of tyrosine kinase activity, and prevents its activity.